Which Framework To Use?

Hello guys, Your help would be much appreciated, i am a student and a startup co founder, i mainly used no code tools before but now I want to start using coding frameworks

I have already set up an aws server and have deployed qdrant

My questions are- 1.Which Framework is best and most importantly easiest and capable of multi agent orchestration? 2. How do i need to connect the backend with frontend, will these frameworks come with some inbuilt tools or do i need to create custom api by using flask or fast api? 3. How do i connect a vector db and crawl sites, do i need to use open source softwares like firecrawl or crawl4ai?

Thanks a lot