Metformin and Endometriosis (for 2025)

I wanted to post this for the 2025 calendar year since I haven’t seen any posts about taking metformin and endometriosis with in the last 6 months. More and more people are reading the NIH study on it, and I wanted to get some perspective of others who have tried this medication. After reading some posts from the last year, not everyone was able to update their experiences on it. I’m apprehensive to start taking it as my OBGYN prescribed it to me after our discussion on it. I’m worried about the side effects and GI upset. I also wanted to know what dosage worked best for you, and what helped to minimize the side effects. I’ve read if you take it at night, that helps lessen the effects. And I’ve read that some people start at 250mg once a day and work their way up to 500mg and some take 500mg 2 or 3x a day. I’m had elevated A1Cs previously at 5.4 as well!

Spam me with your experiences and how you are doing! I’ve also read that others have had better luck to decrease pain with the injectable ozempic/and others like it but wanted to find experiences with metformin since it so much more affordable.