Would this be stupid?

My wife and I both 46yo have about 150k in HYSA and about 400k equity in our home. We both have 401ks through our jobs too me about 120k and her about 160k. Would it be dumb to sell our home to get the 400k then put that and the 150k into VOO? We could get an apartment for cheap. We both have good jobs. I want to somehow make our kids better off in life. Neither one of us came from any money at all and I just want to make a difference for them. Any advice would be awesome!

Current loan on home is 2.5% 15 year, have 10 years left on it. Payment is about 2150 per month.

Thanks!